ENAPURE Healthcare

Severe Gastroenteritis with Fever Gross Blood and Neutrophils in Stool E coli Shigella Salmonella

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-Ceftriaxone (Rocephin) 50-75 mg/kg/day IV/IM q 12-24h, max 4 gm/day OR

-Cefixime (Suprax) 8 mg/kg/day PO bid-qd, max 400 mg/day [susp:

100 mg/5 mL; tabs: 200, 400 mg] OR -Trimethoprim/Sulfamethoxazole (Bactrim, Septra) 10 mg of TMP component/kg/day PO bid x 5-7d, max 320 mg TMP/day [susp per 5 mL: TMP 40 mg/SMX 200 mg; tab DS: TMP 160 mg/SMX 800 mg; tab SS: TMP 80mg/SMX 400 mg]. Salmonella (treat infants and patients with septicemia): -Ceftriaxone (Rocephin) 50-75 mg/kg/day IV/IM q12-24h, max 4 gm/day OR

-Cefixime (Suprax) 8 mg/kg/day PO bid-qd, max 400 mg/day [susp:

100 mg/5 mL; tabs: 200, 400 mg] OR -Ampicillin 100-200 mg/kg/day IV q6h, max 12 gm/day or 50-100 mg/kg/day PO qid x 5-7d, max 4 gm/day [caps: 250, 500 mg; drops: 100 mg/mL; susp: 125 mg/5 mL, 250 mg/5 mL, 500 mg/5 mL] OR

-Trimethoprim/Sulfamethoxazole (Bactrim, Septra) 10 mg TMP/kg/day PO bid x 5-7d, max 320 mg TMP/day [susp per 5 mL: TMP 40 mg/SMX 200 mg; tab DS: TMP 160 mg/SMX 800 mg; tab SS: TMP 80mg/SMX 400 mg] OR -If >18 yrs: Ciprofloxacin (Cipro) 250-750 mg PO q12h or 200-400 mg IV q12h [inj: 200, 400 mg; susp: 100 mg/mL; tabs: 100, 250, 500, 750 mg]